信誉平台开奖体彩中国游戏 飞艇一分钟官网直播 of epigenetic therapeutics to revolutionize medicine
DURECT harnesses epigenetic modulation to treat serious and life-threatening conditions, including acute organ injury and cancer. Our unique approach targeting dysregulated DNA methylation has the potential to change the course of disease and improve patients’ lives.
Epigenetic Modulation
Many types of acute organ injuries and cancers are associated with dysregulation of the epigenome, such as DNA methylation. There is vast potential for epigenetic therapies to address the underlying pathophysiology by mitigating epigenomic dysregulation and helping to improve cellular function or suppress tumor growth.1-3
Alcohol-Associated 飞飞艇手机app看开奖幸运 在线直播开奖网站 (AH)
Clinical Trials
We are currently conducting a Phase 2b study (AHFIRM) in subjects with severe alcohol-associated hepatitis (AH) in more than 60 clinical trial sites across the U.S., EU, U.K., and Australia.
Partner with us
We welcome strategic partnerships to advance our collective goal to meaningfully impact patients’ lives and offer better therapeutic options.
Careers
Join our highly experienced, talented, and collaborative team as we strive to improve the 新幸运飞行艇官方开奖查询 在线官网查询计划历史记录 of human medicine with novel epigenetic therapies.
Press Releases
DURECT Corporation to Present at the Oppenheimer 34th Annual Healthcare Life Sciences Conference
07 Feb, 2024, 18:48 ET CUPERTINO, Calif., Feb. 7, 2024 /PRNewswire/ — DURECT Corporation (Nasdaq: DRRX) today announced that James E. Brown, President and Chief
DURECT Corporation Reports Third Quarter 2023 Financial Results and 视频官方开奖直播体彩飞艇 历史统计开奖号码 Update
13 Nov, 2023, 16:05 ET – Webcast of Earnings Call Today, November 13th at 4:30 p.m. ET – Topline data from AHFIRM trial showed compelling
References
- Argemi J, Latasa MU, Atkinson SR, et al. Defective HNF4alpha-dependent gene expression as a driver of hepatocellular failure in alcoholic hepatitis. Nat Commun. 2019;10(1):3126. doi:10.1038/s41467-019-11004-3
- Mazzone R, Zwergel C, Artico M, et al. The emerging role of epigenetics in human autoimmune disorders. Clin Epigenetics. 2019;11(1):34. doi:10.1186/s13148-019-0632-2
- Herman A, Occean JR, Sen P. Epigenetic dysregulation in cardiovascular aging and disease. J Cardiovasc Aging. 2021;1:10. doi:10.20517/jca.2021.16
- Hassanein T, McClain CJ, Vatsalya V, et al. Safety, Pharmacokinetics, and Efficacy Signals of Larsucosterol (DUR-928) in Alcohol-Associated Hepatitis. Am J Gastroenterol. 2023;10.14309/ajg.0000000000002275.
- Data on File
- Hughes E, Hopkins LJ, Parker R. Correction: Survival from alcoholic hepatitis has not improved over time. PLoS One. 2018;13:e0195857.